PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.
By Christopher Corless, Arin J. Schroeder, D. Griffith, Ajia Town, Laura S. McGreevey, P. Harrell, Sharon Shiraga, Troy Bainbridge, J. Morich, M. Heinrich. Journal of Clinical Oncology, 2005
865 citations recorded by the source corpus.
Subfields: Gastroenterology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/37a5ffad4c1bc9c331590e5f7e4df027aafdb953
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In Gastroenterology
Citations in the corpus
- Molecular correlates of imatinib resistance in gastrointestinal stromal tumors. (2006, methodology): “The doubly mutant V561D D842V kinase proved imatinib-resistant with an IC50 similar to the isolated D842V isoform (Fig 6).(17)”