The CYP2D6 Activity Score: Translating Genotype Information into a Qualitative Measure of Phenotype

By A. Gaedigk, Sd Simon, R. Pearce, L. Bradford, M. Kennedy, J. Leeder. Clinical pharmacology and therapy, 2008

765 citations recorded by the source corpus.

Subfields: Pharmacology, Spectroscopy, Statistics and Probability

View Paper: https://www.semanticscholar.org/paper/378dd5e7d9e3ce614ce1b5a21baac18f4f62b9fe

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Citations in the corpus

• Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC®) for CYP2D6 and CYP2C19 Genotypes and Dosing of Tricyclic Antidepressants: 2016 Update (2017, background): “5 for decreased function, and 0 for no function alleles (see Supplemental Material; CYP2D6 Allele Definition Table (1)) (2, 7).”