Employment of reactive oxygen species to enhance astaxanthin formation in Chlorella zofingiensis in heterotrophic culture

By Po-Fung Ip, Feng Chen. 2005

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Heterotrophic cultures of microalgae: metabolism and potential products. (2011, background): “Its strong antioxidant character makes it a nutraceutical product (food or nutritional supplement that may improve health) and may prevent some cancers (Hagen et al., 2001; Ma and Chen, 2001; Pulz and Gross, 2004; Del Rio et al., 2005; Ip and Chen, 2005a; Wang and Peng, 2008).”
Sugar-based growth, astaxanthin accumulation and carotenogenic transcription of heterotrophic Chlorella zofingiensis (Chlorophyta) (2008, methodology): “4 mg l 1 (this study), which may be further enhanced by employment of reactive oxygen species as described in our previous study [31,32] or by optimization of fermentative medium [33].”
The accumulation and metabolism of astaxanthin in Scenedesmus obliquus (Chlorophyceae) (2008, background): “One is the factors that enhance the astaxanthin yield in algae such as culturing media [14], higher temperature [15], intensive illumination [16], oxidative stress [17,18] and salt stress”