MLST revisited: the gene-by-gene approach to bacterial genomics
By Martin C. J. Maiden, M. J. V. Rensburg, James E. Bray, S. Earle, Suzanne A. Ford, Keith A. Jolley, N. McCarthy. Nature Reviews Microbiology, 2013
689 citations recorded by the source corpus.
Subfields: Clinical Biochemistry, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/35411f5ee26b1e4b2aa9d3bb123904cfb0c57bf5
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In Molecular Biology
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Citations in the corpus
- The EnteroBase user's guide, with case studies on Salmonella transmissions, Yersinia pestis phylogeny, and Escherichia core genomic diversity (2019, methodology): “…on a daily basis with the schemes that are maintained at PubMLST (https:// pubmlst.org/). wgMLST, whole genome multilocus sequence typing (Maiden et al. 2013); cgMLST, core genome multilocus sequence typing (Mellmann et al. 2011); rMLST, ribosomal multilocus sequence typing (Jolley et…”
- The Salmonella In Silico Typing Resource (SISTR): An Open Web-Accessible Tool for Rapidly Typing and Subtyping Draft Salmonella Genome Assemblies (2016, methodology): “In addition to providing genoserotyping-based serovar prediction [13,14], this resource integrates several additional sequence-based typing analyses that include MLST [29], rMLST [30], and cgMLST [23,24] into a single web-based tool.”
- ClonalFrameML: Efficient Inference of Recombination in Whole Bacterial Genomes (2015, background): “This gene been described as one of only two integration sites for prophage FCD27 [67].”
- GrapeTree: visualization of core genomic relationships among 100,000 bacterial pathogens (2017, neutral): “…ribosomal proteins (rMLST) (Jolley et al. 2012), thousands of core genes that are present in most isolates of a species or genus (core genome MLST, cgMLST) (Mellmann et al. 2011; Maiden et al. 2013;Mouraetal.2016),orevenallthegenesintheentiregenome (whole genome MLST, wgMLST) (Nadon et al. 2017).”
- PHYLOViZ 2.0: providing scalable data integration and visualization for multiple phylogenetic inference methods (2017, methodology): “While traditional MLST relies on a few genes for discriminating bacterial isolates, the advent of High-Throughput Sequencing (HTS) allowed analyzing thousands of loci and is being presented as the ultimate tool for defining bacterial clones with application in clinical settings (Carriço et al., 2013”