Interleukin-6 signaling pathway in targeted therapy for cancer.

By Yuqi Guo, Feng Xu, Tianjian Lu, Z. Duan, Zhan Zhang. Cancer Treatment Reviews, 2012

688 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/348920bc8a614c8cb8b14a5e2ed9dde9680a6833

How researchers see this paper

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In Oncology

1. Neeraj Kumari
2. A. Bhatt
3. B. Dwarakanath
4. Asmita Das

Citations in the corpus

• Shared Risk Factors in Cardiovascular Disease and Cancer (2016, background): “Overexpression of interleukin-6 has been shown to inhibit cancer cell apoptosis, stimulate angiogenesis, and have a role in drug resistance, leading to tumor progression.(43)”
• Role of interleukin-6 in cancer progression and therapeutic resistance (2016, background): “Patients with high levels of circulating IL-6 are generally associated with poor prognosis and shorter survival, whilst a lower level of IL-6 is associated with better response to therapy [14, 15].”