Risk factors, prevention, and management of postoperative recurrence after resection of hepatocellular carcinoma.

By R. Poon, S. Fan, J. Wong. Annals of Surgery, 2000

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Risk factors contributing to early and late phase intrahepatic recurrence of hepatocellular carcinoma after hepatectomy. (2003, background): “Although remarkable advances in surgical and imaging modalities have improved the prognosis of hepatocellular carcinoma (HCC) patients [1], the high incidence of intrahepatic recurrence remains a major challenge in HCC therapy [2,3].”
Early and Late Recurrence After Liver Resection for Hepatocellular Carcinoma: Prognostic and Therapeutic Implications (2006, result): “The risk deriving from this aggressive attitude in the presence of an intrahepatic recurrence, if applied in selected patients, is quite low; in our experience, including 28 resections for recurrence; the mortality was nil, as in the near totality of the series reported in the literature.(15) The ri”
Long-Term Survival and Pattern of Recurrence After Resection of Small Hepatocellular Carcinoma in Patients With Preserved Liver Function: Implications for a Strategy of Salvage Transplantation (2002, background): “Both factors may be associated with a high risk of multicentric recurrence.(32) The survival results of patients with concomitant oligocentric tumors and cirrhosis were particularly poor compared with other subgroups, with a 5-year diseasefree survival rate of 0%.”