Foldscope: Origami-Based Paper Microscope
By James S. Cybulski, J. Clements, Manu Prakash. PLoS ONE, 2014
339 citations recorded by the source corpus.
Here we describe an ultra-low-cost origami-based approach for large-scale manufacturing of microscopes, specifically demonstrating brightfield, darkfield, and fluorescence microscopes. Merging principles of optical design with origami enables high-volume fabrication of microscopes from 2D media. Flexure mechanisms created via folding enable a flat compact design. Structural loops in folded paper provide kinematic constraints as a means for passive self-alignment. This light, rugged instrument can survive harsh field conditions while providing a diversity of imaging capabilities, thus serving wide-ranging applications for cost-effective, portable microscopes in science and education.
Subfields: Biomedical Engineering, Mechanical Engineering, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/33d8d5858f743546414e9a411f847eb1efe1947f
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Biomedical Engineering
In Mechanical Engineering
In Molecular Biology
Citations in the corpus
- Open Labware: 3-D Printing Your Own Lab Equipment (2015, background): “One next step in this evolution may be to add low-cost fluorescence capability through the addition of a ultraviolet light-emitting diode (UV-LED) and the appropriate filters, perhaps inspired by materials used in the less than US$1 fluorescence-capable Foldscope [24].”
- A review of origami applications in mechanical engineering (2016, methodology): “Another application of optigami is the Foldscope, which is a flat microscope that can be used to achieve 2000 magnification and submicron resolution.(28) This device can be assembled in about 10min from a flat Figure 8.”