Frequency of Gestational Diabetes Mellitus at Collaborating Centers Based on IADPSG Consensus Panel–Recommended Criteria

By D. Sacks, D. Hadden, M. Maresh, C. Deerochanawong, A. Dyer, Boyd E. Metzger, L. Lowe, D. Coustan, M. Hod, J. Oats and 2 more. Diabetes Care, 2012

673 citations recorded by the source corpus.

OBJECTIVE To report frequencies of gestational diabetes mellitus (GDM) among the 15 centers that participated in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study using the new International Association of the Diabetes and Pregnancy Study Groups (IADPSG) criteria. RESEARCH DESIGN AND METHODS All participants underwent a 75-g oral glucose tolerance test between 24 and 32 weeks’ gestation. GDM was retrospectively classified using the IADPSG criteria (one or more fasting, 1-h, or 2-h plasma glucose concentrations equal to or greater than threshold values of 5.1, 10.0, or 8.5 mmol/L, respectively). RESULTS Overall frequency of GDM was 17.8% (range 9.3–25.5%). There was substantial center-to-center variation in which glucose measures met diagnostic thresholds. CONCLUSIONS Although the new diagnostic criteria for GDM apply globally, center-to-center differences occur in GDM frequency and relative diagnostic importance of fasting, 1-h, and 2-h glucose levels. This may impact strategies used for the diagnosis of GDM.

Subfields: Endocrinology, Diabetes and Metabolism, Obstetrics and Gynecology

View Paper: https://www.semanticscholar.org/paper/33860fc589bd84fdc2c0193da639961732e91499

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In Obstetrics and Gynecology

1. M. Schmidt
2. E. Wendland
3. M. A. Campos
4. B. Duncan
5. M. Falavigna
6. M. Torloni
7. J. Trujillo
8. M. L. Dode

Citations in the corpus

• Gestational diabetes and pregnancy outcomes - a systematic review of the World Health Organization (WHO) and the International Association of Diabetes in Pregnancy Study Groups (IADPSG) diagnostic criteria (2012, background): “However, as this rate in HAPO varied from 24% (Thailand) to 74% (Barbados)[23], whether these differences resulted from incomplete fasting or from other specific study or population particularity cannot be concluded from current information.”