Deep Brain Stimulation for Parkinson Disease

By J. Bronstein, M. Tagliati, R. Alterman, Andres M. Lozano, J. Volkmann, A. Stefani, Fay B. Horak, M. Okun, K. Foote, P. Krack and 11 more. Archives of Neurology, 2010

933 citations recorded by the source corpus.

Objective To provide recommendations to patients, physicians, and other health care providers on several issues involving deep brain stimulation (DBS) for Parkinson disease (PD). Data Sources and Study Selection An international consortium of experts organized, reviewed the literature, and attended the workshop. Topics were introduced at the workshop, followed by group discussion. Data Extraction and Synthesis A draft of a consensus statement was presented and further edited after plenary debate. The final statements were agreed on by all members. Conclusions (1) Patients with PD without significant active cognitive or psychiatric problems who have medically intractable motor fluctuations, intractable tremor, or intolerance of medication adverse effects are good candidates for DBS. (2) Deep brain stimulation surgery is best performed by an experienced neurosurgeon with expertise in stereotactic neurosurgery who is working as part of a interprofessional team. (3) Surgical complication rates are extremely variable, with infection being the most commonly reported complication of DBS. (4) Deep brain stimulation programming is best accomplished by a highly trained clinician and can take 3 to 6 months to obtain optimal results. (5) Deep brain stimulation improves levodopa-responsive symptoms, dyskinesia, and tremor; benefits seem to be long-lasting in many motor domains. (6) Subthalamic nuclei DBS may be complicated by increased depression, apathy, impulsivity, worsened verbal fluency, and executive dysfunction in a subset of patients. (7) Both globus pallidus pars interna and subthalamic nuclei DBS have been shown to be effective in addressing the motor symptoms of PD. (8) Ablative therapy is still an effective alternative and should be considered in a select group of appropriate patients.

Subfields: Neurology

View Paper: https://www.semanticscholar.org/paper/336ee8040691a6202ba366feb34420c0a99fdac3

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Citations in the corpus

Clinical Practice of Forensic Neuropsychology: An Evidence-Based Approach (2012, background): “In the case of epilepsy (Brodie et al., 1997), deep brain stimulation (Bronstein et al., 2011), and select other conditions, a presurgical neuropsychological evaluation is considered part of standard care.”
Closed-loop deep brain stimulation is superior in ameliorating parkinsonism. (2011, positive): “, frequency, pulse width, and intensity) are determined by a highly trained clinician and the initial programming can take up to 6 months before obtaining optimal results (Bronstein et al., 2011; Volkmann et al., 2006).”
Towards fog-driven IoT eHealth: Promises and challenges of IoT in medicine and healthcare (2018, background): “…provide highly-controlled electrical impulses into deep brain regions to reduce movements symptoms in motor disorders such as Parkinson’s disease [112] and Essential Tremors [113], and 3) cochlea implants that stimulate electrodes placed inside the inner-ear to store hearing functions [114].”
The Neurostimulationist will see you now: prescribing direct electrical stimulation therapies for the human brain in epilepsy and beyond (2024, background): “…disease to obsessive compulsive disorder (OCD) to epilepsy and depression (Berger and Ojemann, 1992; Rizzone et al., 2001; Mayberg et al., 2005; Bronstein et al., 2011; Rolston et al., 2011; Bourne et al., 2012; Lozano and Lipsman, 2013; Revell, 2015; Herrington et al., 2016; Lozano et al.,…”