Biomedical Applications of Biodegradable Polymers

By B. Ulery, L. Nair, C. Laurencin. Journal of Polymer Science Part B: Polymer Physics, 2011

1,975 citations recorded by the source corpus.

Utilization of polymers as biomaterials has greatly impacted the advancement of modern medicine. Specifically, polymeric biomaterials that are biodegradable provide the significant advantage of being able to be broken down and removed after they have served their function. Applications are wide ranging with degradable polymers being used clinically as surgical sutures and implants. In order to fit functional demand, materials with desired physical, chemical, biological, biomechanical and degradation properties must be selected. Fortunately, a wide range of natural and synthetic degradable polymers has been investigated for biomedical applications with novel materials constantly being developed to meet new challenges. This review summarizes the most recent advances in the field over the past 4 years, specifically highlighting new and interesting discoveries in tissue engineering and drug delivery applications.

Subfields: Biomaterials, Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/3309e4f021f4fc8958b591c1091059834c2071cf

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. K. Yue
2. Ali Tamayol
3. Ali Khademhosseini
4. H. Rashid
5. Z. Sheikh
6. V. Verma
7. Elbay Malikmammadov
8. T. E. Tanir

In Biomedical Engineering

1. Ali Tamayol
2. K. Yue
3. Ali Khademhosseini
4. H. Rashid
5. Z. Sheikh
6. V. Verma
7. Zohaib Khurshid
8. M. Glogauer

Citations in the corpus

• Microbial enzymes: industrial progress in 21st century (2016, background): “Biopolymers, such as polyesters, polycarbonates and polyphosphates are used in various biomedical applications, e.g., orthopedic devices, tissue engineering, adhesion barriers, control drug delivery, etc. (Gunatillake and Adhikari 2003; Ulery et al. 2011).”
• Biodegradable Materials for Bone Repair and Tissue Engineering Applications (2015, background): “Their biodegradability and controlled degradation rates are highly beneficial for clinical applications [180,181].”
• Drug Delivery Systems and Materials for Wound Healing Applications (2018, positive): “Upon degradation, PLGA breaks down to its original monomers, PLA will be cleared through the tricarboxylic acid (TCA) cycle and PGA is either removed from the body or converted into other metabolites[146, 155].”
• Alginate in Wound Dressings (2018, background): “are non-toxic, readily available, biodegradable, biocompatible, and non-immunogenic [7,8].”