DNA double-strand break repair-pathway choice in somatic mammalian cells

By R. Scully, Arvind Panday, Rajula Elango, Nicholas A. Willis. Nature reviews. Molecular cell biology, 2019

1,197 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/328edcedb9c7624be626e97beee54b2db041b12e

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In Molecular Biology

1. Ruixue Huang
2. Pingkun Zhou

Citations in the corpus

• DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy (2021, background): “While the c-NHEJ and HR pathways are primarily responsible for repairing DSBs of DNA, alternative end joining (alt-EJ) was considered responsible for residual DSBs that c-NHEJ and HR are unable to repair.(312,313) However, it is unsure whether alt-EJ represents a standing pathway or only the endjoin”