TMP21 is a presenilin complex component that modulates γ-secretase but not ɛ-secretase activity

By Fusheng Chen, H. Hasegawa, G. Schmitt-Ulms, T. Kawarai, Christopher Bohm, T. Katayama, Yongjun Gu, N. Sanjo, M. Glista, E. Rogaeva and 10 more. Nature, 2006

233 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics, Physiology

View Paper: https://www.semanticscholar.org/paper/3280dc278f31d231b052f06e82a76ee5bca5cb23

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. E. Andersson
2. Rickard Sandberg
3. U. Lendahl
4. Sarah A. Teichmann

Citations in the corpus

• Notch signaling: simplicity in design, versatility in function (2011, background): “…as CD147 (also known as BSG), transmembrane protein 21 (Tmp21, also known as Tmed10) and - secretase activating protein (GSAP, also known as Pion) (Chen et al., 2006; He et al., 2010; Zhou et al., 2006), have also been identified but the mechanistic basis for their differential effects on Notch…”