Facilitation of brain stimulation reward byΔ9-tetrahydrocannabinol
By Eliot L. Gardner, W. Paredes, Diane M. Smith, A. Donner, C. Milling, D. Cohen, D. Morrison. Psychopharmacology, 2006
114 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Pharmacology, Physiology
View Paper: https://www.semanticscholar.org/paper/3261c6d17578923c47088399767de3dc4eb7652f
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In Cellular and Molecular Neuroscience
In Pharmacology
In Physiology
Citations in the corpus
- The endocannabinoid system and the brain. (2013, background): “…investigators have reported that THC (as well as other abused drugs such as cocaine) reduces the threshold for electrical brain stimulation reward (Gardner et al. 1988), but other investigators report that it increases the 6.10 Mechoulam · Parker Changes may still occur before final publication…”
- The Endocannabinoid System as an Emerging Target of Pharmacotherapy (2006, background): “…THC increases extracellular dopamine levels in the nAc via activation of CB1 receptors (Chen et al., 1990; Tanda et al., 1999) and also lowers the reward threshold for electrical brain stimulation (Gardner et al., 1988), a phenomenon known to involve activation of the mesolimbic dopamine system.”