Extraction, isolation and characterization of bioactive compounds from plants' extracts.
By S. Sasidharan, Yeng Chen, D. Saravanan, K. Sundram, L. Y. Latha. African Journal of Traditional Complementary and Alternative Medicines, 2010
1,548 citations recorded by the source corpus.
Natural products from medicinal plants, either as pure compounds or as standardized extracts, provide unlimited opportunities for new drug leads because of the unmatched availability of chemical diversity. Due to an increasing demand for chemical diversity in screening programs, seeking therapeutic drugs from natural products, interest particularly in edible plants has grown throughout the world. Botanicals and herbal preparations for medicinal usage contain various types of bioactive compounds. The focus of this paper is on the analytical methodologies, which include the extraction, isolation and characterization of active ingredients in botanicals and herbal preparations. The common problems and key challenges in the extraction, isolation and characterization of active ingredients in botanicals and herbal preparations are discussed. As extraction is the most important step in the analysis of constituents present in botanicals and herbal preparations, the strengths and weaknesses of different extraction techniques are discussed. The analysis of bioactive compounds present in the plant extracts involving the applications of common phytochemical screening assays, chromatographic techniques such as HPLC and, TLC as well as non-chromatographic techniques such as immunoassay and Fourier Transform Infra Red (FTIR) are discussed.
Subfields: Endocrinology, Diabetes and Metabolism, Food Science, Plant Science
View Paper: https://www.semanticscholar.org/paper/317de4807ec3712ea53e851444bc38d55705505c
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology, Diabetes and Metabolism
In Food Science
In Plant Science
Citations in the corpus
- New Perspectives on How to Discover Drugs from Herbal Medicines: CAM's Outstanding Contribution to Modern Therapeutics (2013, background): “Phytochemical study of extracts of herbal preparations or botanicals involves isolation, structure/composition elucidation, and bioactivity evaluation [39].”
- Preparation of Medicinal Plants: Basic Extraction and Fractionation Procedures for Experimental Purposes (2020, methodology): “It involves the use of chromatographic techniques, identification techniques, and chemical analysis to characterize a pharmacologically active compound from a medicinal plant.[4,5] Immunoassay.”