Independent Codes for Spatial and Episodic Memory in Hippocampal Neuronal Ensembles

By Stefan Leutgeb, J. Leutgeb, C. A. Barnes, Edvard I. Moser, Bruce L. McNaughton, May-Britt Moser. Science, 2005

869 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/3156ca1332d2cbb54b3a6baec0dc2c35c1887970

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Hippocampal Sharp Waves and Reactivation during Awake States Depend on Repeated Sequential Experience (2006, background): “Such cell assemblies have been directly observed in theta during behavior (Wilson and McNaughton, 1993; Harris et al., 2003; Leutgeb et al., 2005; Wills et al., 2005) and reactivation of those assemblies have been observed during subsequent sleep states (Pavlides and Winson, 1989; Wilson and McNaugh”
Non-commercial Research and Educational Use including without Limitation Use in Instruction at Your Institution, Sending It to Specific Colleagues That You Know, and Providing a Copy to Your Institution's Administrator. All Other Uses, Reproduction and Distribution, including without Limitation Comm (2005, neutral): “…with heteronuclear decoupling, multiple quantum NMR (MQ–NMR) techniques , computer experiments such as molecular dynamics or Monte Carlo type simulations to estimate the degree of orientational order, and the use of 'magic mixtures' in combination with simple phenomenological models to…”
CA3 Retrieves Coherent Representations from Degraded Input: Direct Evidence for CA3 Pattern Completion and Dentate Gyrus Pattern Separation (2014, result): “Thus, the present study is a critical complement to the Leutgeb study, as well as other studies from those investigators (Leutgeb et al., 2004; Leutgeb et al., 2005).”
Hippocampal “time cells” bridge the gap in memory for discontiguous events (2011, neutral): “The cross-correlation analysis indicated that most neurons (90%, 46/51) that retimed in block 2 maintained the altered pattern through block 3, similar to the hysteresis reported for partial remapping of place cells (Leutgeb et al., 2005a).”
Timing and efficacy of transmitter release at mossy fiber synapses in the hippocampal network (2006, neutral): “separation (amplification of differences between input patterns; [51, 52 ]).”
Anatomical gradients of adult neurogenesis and activity: young neurons in the ventral dentate gyrus are activated by water maze training (2009, neutral): “…genes contribute to signaling cascades required for induction of long-term synaptic plasticity and consolidation of long-term memory (Kubik et al., 2007), and their expression patterns parallel those seen physiologically in ''place cells'' (Guzowski et al., 1999; Leutgeb et al., 2005).”
Place cells, grid cells, and the brain's spatial representation system. (2008, background): “Two forms of remapping have been reported (Leutgeb et al. 2005b): The cell population may undergo complete orthogonalization of both firing locations and firing rates (global remapping), or the rate distribution may be changed selectively in the presence of stable firing locations (rate remapping).”
Progressive transformation of hippocampal neuronal representations in "morphed" environments. (2005, methodology): “The latter type of remapping in CA1 is accompanied by strong but exclusive rate remapping in CA3 (Leutgeb et al., 2005).”
Tracking the Flow of Hippocampal Computation: Pattern Separation, Pattern Completion, and Attractor Dynamics (2015, background): “Such global remapping in CA3, such as that produced by bringing the rat to a completely different environment (Colgin et al., 2010; Leutgeb et al., 2005; but see Knierim, 2003), would show the pattern separation properties of CA3 and could be depicted by adding a new attractor ring to the diagram th”
Dissociating the past from the present in the activity of place cells (2006, background): “These findings acquire a consistent light when one takes into consideration those of Leutgeb et al. (2005) and their interpretation.”
Episodic-like memory trace in awake replay of hippocampal place cell activity sequences (2015, background): “I have now shown that replays also encode non-spatial information in temporally compressed firing rates, revealing that global and rate remapping mechanisms during running (Leutgeb et al., 2005; Takahashi, 2013) are preserved in the temporally compressed replays that occur during brief periods of im”