Practices of Liver Biopsy in France: Results of a Prospective Nationwide Survey

By J. Cadranel, P. Rufat, F. Degos. Hepatology, 2000

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Non-invasive evaluation of liver fibrosis using transient elastography. (2008, background): “However, liver biopsy is an invasive and painful procedure, often with poor patient acceptance and also carries a significant, although small risk of life-threatening complications [4,5].”
WFUMB guidelines and recommendations for clinical use of ultrasound elastography: Part 3: liver. (2015, background): “Although liver biopsy has long been the gold standard, it is an invasive procedure with potential complications such as bleeding and severe pain (Bravo et al. 2001; Cadranel et al. 2000).”
A simple noninvasive index can predict both significant fibrosis and cirrhosis in patients with chronic hepatitis C (2003, neutral): “014 African Americans 16 (8) 17 (22) Others 7 (4) 5 (6) Unknown 18 (9) 8 (10) Drinking history, n (%) Current drinker 26 (14) 8 (10) .”
FIB‐4: An inexpensive and accurate marker of fibrosis in HCV infection. comparison with liver biopsy and fibrotest (2007, methodology): “We reviewed our computerized files of HCV-infected patients attending our unit and selected all the cases corresponding to the following criteria: (1) anti HCV- and HCV-RNA–positive; (2) LB prior to any antiviral therapy; (3) laboratory assessments allowing FIB-4 calculation (AST, ALT, platelet coun”