Robust expansion of human hepatocytes in Fah−/−/Rag2−/−/Il2rg−/− mice

By H. Azuma, N. Paulk, Aarati R. Ranade, C. Dorrell, M. Al‐Dhalimy, E. Ellis, S. Strom, M. Kay, M. Finegold, M. Grompe. Nature Biotechnology, 2007

804 citations recorded by the source corpus.

Subfields: Hepatology, Surgery

View Paper: https://www.semanticscholar.org/paper/30c51be1e85456cc02090e44709bdd3f11e69883

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Citations in the corpus

• Organogenesis and development of the liver. (2010, background): “Recent work has shown that up to 90% of the mouse hepatic parenchyma can be replaced with human hepatocytes when such cells are transferred into immunocompromised fumarylacetoacetate hydrolase (Fah)-deficient animals (Azuma et al., 2007; Bissig et al., 2007).”