Modulatory effects of fenugreek seeds powder on the histopathology, oxidative status, and immune related gene expression in Nile tilapia (Oreochromis niloticus) infected with Aeromonas hydrophila

By E. Moustafa, Mahmoud A. O. Dawood, Doaa H. Assar, A. Omar, Z. Elbialy, F. Farrag, Mustafa Shukry, Mohamed M. Zayed. 2020

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Abstract The present trial investigated the effects of dietary fenugreek on the histopathology, oxidative status, and immune-related gene expression in Nile tilapia (Oreochromis niloticus) (15 ± 0.5 g) infected with Aeromonas hydrophila. Fish were fed two diets with or without fenugreek supplementation at 3%. The trial was lasted for 8 weeks then fish were divided into four groups; the first and fourth groups were intra-peritoneally injected with phosphate buffer saline (PBS) while the second and third groups were challenged with sublethal dose of A. hydrophila. At 6 h, 24 h and 1-week post challenge, several serum immune and immune-related gene expressions and antioxidant defense parameters as well as the histopathological alterations were evaluated. The results indicated that administration of fenugreek supplemented diets could significantly increase the growth performance parameters and decreased the feed conversion ratio as compared to the non-supplemented groups (P

Subfields: Aquatic Science, Immunology, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/30c1eba01c596e1e80d30b15f89709c0cd0874c1