Selective Deposition of Proteins and Cells in Arrays of Microwells

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Dynamic single cell culture array. (2006, methodology): “Other techniques that allow single cell arrays of adherent cells in most cases require protein patterning of the surface or chemical treatments [ 1 ].”
A Microfluidic Chip for Cell Patterning Utilizing Paired Microwells and Protein Patterns † (2016, methodology): “reported a convenient method for cell patterning using microwells coated by fibronectin, a commonly used cell adhesive protein [38].”
dPCR: A Technology Review (2018, background): “The oil phase preferentially wets the top of the array and creates a meniscus that displaces the aqueous phase; however, the oil/aqueous phase/solid triple line gets pinned at transitions between hydrophobic and hydrophilic areas [58,67].”
3D Self-Organized Microvascular Model of the Human Blood-Brain Barrier with Endothelial Cells, Pericytes and Astrocytes (2018, background): “Accordingly, distinct surface modifications that could reduce non-specific absorption include coating the PDMS surface with bovine serum albumin (BSA) [68], grafting with anti-fouling molecules [69], or silanization [70].”
Soft lithography in biology and biochemistry. (2001, methodology): “We have developed a method for patterning the adhesion of cells in high-density arrays of microscopic wells (ca 10,000 wells/cm2, 50-μm well diameter) that are fabricated by replica molding of PDMS against a master of photoresist (223).”