Modern homology modeling of G-protein coupled receptors: which structural template to use?

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Multi-State Modeling of G-protein Coupled Receptors at Experimental Accuracy (2021, methodology): “For example, GPCR models predicted using templates with sequence identities higher than 20%–40% were assumed to be confident.(24,33,34) Likewise, it may be used to infer the success of modeling prior to the active state modeling via”
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors—An Update (2011, background): “From a different perspective, Mobarec et al. (2009) concluded that based on sequence identity the currently available structures may only provide reasonable homology models for a small minority of class A GPCRs.”
Assessment and Challenges of Ligand Docking into Comparative Models of G-Protein Coupled Receptors (2013, background): “…multiple models based on different templates provides a better opportunity to sample the correct conformation and this is leveraged here [12], the generation of a smaller but improved conformational receptor ensemble could benefit from using multiple template structures in a single model [45].”