Twenty five year mortality of a community cohort with schizophrenia
By Steve Brown, Miranda Kim, C. Mitchell, H. Inskip. British Journal of Psychiatry, 2010
604 citations recorded by the source corpus.
Background People with schizophrenia have significantly raised mortality but we do not know how these mortality patterns in the UK have changed since the 1990s. Aims To measure the 25-year mortality of people with schizophrenia with particular focus on changes over time. Method Prospective record linkage study of the mortality of a community cohort of 370 people with schizophrenia. Results The cohort had an all-cause standardised mortality ratio of 289 (95% CI 247–337). Most deaths were from the common causes seen in the general population. Unnatural deaths were concentrated in the first 5 years of follow-up. There was an indication that cardiovascular mortality may have increased relative to the general population (P = 0.053) over the course of the study. Conclusions People with schizophrenia have a mortality risk that is two to three times that of the general population. Most of the extra deaths are from natural causes. The apparent increase in cardiovascular mortality relative to the general population should be of concern to anyone with an interest in mental health.
Subfields: Cardiology and Cardiovascular Medicine, Clinical Psychology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/301ab99e48a5fdd579d776311d2bf67f65e468d1
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In Clinical Psychology
In Psychiatry and Mental health
Citations in the corpus
- Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care (2011, background): “52 World Psychiatry 10:1 - February 2011 A number of reviews and studies have shown that people with severe mental illness (SMI), including schizophrenia, bipolar disorder, schizoaffective disorder and major depressive disorder, have an excess mortality, being two or three times as high as that in t”
- Effects of antipsychotics, antidepressants and mood stabilizers on risk for physical diseases in people with schizophrenia, depression and bipolar disorder (2015, background): “and mortality than their counterparts in the general population (1,5,6,11,96-99).”