Circadian control of the immune system
By C. Scheiermann, Y. Kunisaki, P. Frenette. Nature reviews. Immunology, 2013
1,017 citations recorded by the source corpus.
Circadian rhythms, which have long been known to play crucial roles in physiology, are emerging as important regulators of specific immune functions. Circadian oscillations of immune mediators coincide with the activity of the immune system, possibly allowing the host to anticipate and handle microbial threats more efficiently. These oscillations may also help to promote tissue recovery and the clearance of potentially harmful cellular elements from the circulation. This Review summarizes the current knowledge of circadian rhythms in the immune system and provides an outlook on potential future implications.
Subfields: Complementary and alternative medicine, Endocrine and Autonomic Systems, Physiology
View Paper: https://www.semanticscholar.org/paper/301a33e68f628b6dd622ccdc8e15f8bd1f57d6eb
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In Physiology
Citations in the corpus
- Leukocyte migration into inflamed tissues. (2014, background): “Similarly, despite much interest in the impact of circadian rhythm on inflammatory responses (reviewed by [Scheiermann et al., 2013]), it remains unclear whether and how different endothelial cells, and their associated pericytes, are subjected to circadian modulation of transcription and how this i”
- Neutrophil: A Cell with Many Roles in Inflammation or Several Cell Types? (2018, background): “This regulation of neutrophil migration into tissues follows a circadian pattern (Scheiermann et al., 2013; see below).”