Micromechanics senses biomolecules

By R. Raiteri, M. Grattarola, R. Berger. 2002

85 citations recorded by the source corpus.

Abstract How can microelectromechanical systems (MEMS) experts support molecular biologists in studying DNA hybridization? Cantilever-based devices are an example of how a ‘simple’ sensor can be tailored by microfabrication techniques and used to achieve an unprecedented performance. We review fascinating experiments, which use different mechanical transduction principles for detecting and analyzing small quantities of materials. The principles of these experiments allow biologists to study surface biochemistry on a nano-scale and offer new, exciting opportunities in developing microscopic biomedical analysis systems with unique characteristics. Cantilever sensors rely on relatively well known and simple transduction principles, and have attracted the interest of many researchers. This is, at least in part, because of the merging of silicon microfabrication techniques and surface functionalization biochemistry, together with the development of multi-cantilever sensing methods offering new opportunities in physical and (bio)chemical sensing.

Subfields: Atomic and Molecular Physics, and Optics, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/2fbee5d5364dbe433fde597a2226eba1f5ca51bd

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1. J. Simaika
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4. Mark John Costello
5. Christos Arvanitidis
6. E. Regan
7. Haigen Xu
8. S. Barber-Meyer

Citations in the corpus

• Building capacity in biodiversity monitoring at the global scale (2017, background): “Using such technology would allow the generation of a smellscape of the environment, and may help detect biomolecules, such as pheromones or other species-specific molecules (Raiteri et al. 2002).”