Dietary fiber and prebiotics and the gastrointestinal microbiota
By H. Holscher. Gut microbes, 2017
1,478 citations recorded by the source corpus.
ABSTRACT The gastrointestinal microbiota has an important role in human health, and there is increasing interest in utilizing dietary approaches to modulate the composition and metabolic function of the microbial communities that colonize the gastrointestinal tract to improve health, and prevent or treat disease. One dietary strategy for modulating the microbiota is consumption of dietary fiber and prebiotics that can be metabolized by microbes in the gastrointestinal tract. Human alimentary enzymes are not able to digest most complex carbohydrates and plant polysaccharides. Instead, these polysaccharides are metabolized by microbes which generate short-chain fatty acids (SCFAs), including acetate, propionate, and butyrate. This article reviews the current knowledge of the impact of fiber and prebiotic consumption on the composition and metabolic function of the human gastrointestinal microbiota, including the effects of physiochemical properties of complex carbohydrates, adequate intake and treatment dosages, and the phenotypic responses related to the composition of the human microbiota.
Subfields: Molecular Biology, Nutrition and Dietetics, Physiology
View Paper: https://www.semanticscholar.org/paper/2f305ac32bbdc6581c9291e2e488ab627038a5bb
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In Molecular Biology
Citations in the corpus
- Effect of Diet on the Gut Microbiota: Rethinking Intervention Duration (2019, background): “Biotransformation of these food components often results in the production of short-chain fatty acids (SCFAs), including acetate, propionate and butyrate [57].”