Epidemiology and Molecular Pathology of Gallbladder Cancer
By E. Lazcano-Ponce, J. Miquel, N. Muñoz, R. Herrero, C. Ferrecio, I. Wistuba, P. A. Ruiz, Gerardo Aristi Urista, F. Nervi. Ca, 2001
864 citations recorded by the source corpus.
Gallbladder cancer is usually associated with gallstone disease, late diagnosis, unsatisfactory treatment, and poor prognosis. We report here the worldwide geographical distribution of gallbladder cancer, review the main etiologic hypotheses, and provide some comments on perspectives for prevention. The highest incidence rate of gallbladder cancer is found among populations of the Andean area, North American Indians, and Mexican Americans. Gallbladder cancer is up to three times higher among women than men in all populations. The highest incidence rates in Europe are found in Poland, the Czech Republic, and Slovakia. Incidence rates in other regions of the world are relatively low. The highest mortality rates are also reported from South America, 3.5–15.5 per 100,000 among Chilean Mapuche Indians, Bolivians, and Chilean Hispanics. Intermediate rates, 3.7 to 9.1 per 100,000, are reported from Peru, Ecuador, Colombia, and Brazil. Mortality rates are low in North America, with the exception of high rates among American Indians in New Mexico (11.3 per 100,000) and among Mexican Americans.
Subfields: Pathology and Forensic Medicine, Plant Science, Surgery
View Paper: https://www.semanticscholar.org/paper/2eaec33bae24206c7657035579bc2e4b885fff9a
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Citations in the corpus
- Gallbladder cancer worldwide: Geographical distribution and risk factors (2006, background): “Gallbladder cancer (GC) is a relatively rare neoplasm that differs from other cancers of the digestive tract, as being several-fold more common in women than in men.(1) Symptoms and signs of GC are not specific and often appear late in the clinical course of the disease.”
- Epidemiology of Gallbladder Disease: Cholelithiasis and Cancer (2012, background): “1 per 100,000) occur elsewhere in South Americans of Indian descent, and in Israel (5/100,000) and Japan (7/100,000).(184) The frequency is increasing in Shanghai, China and now accounts for the most frequent gastrointestinal malignancy and is a substantial cause of mortality.”