Simple selection criteria for drug-like chemical matter.

By I. Muegge, S. Heald, D. R. Brittelli. Journal of Medicinal Chemistry, 2001

1,138 citations recorded by the source corpus.

Subfields: Computational Theory and Mathematics, Environmental Chemistry, Spectroscopy

View Paper: https://www.semanticscholar.org/paper/2dea885d33bd8f2115d7cc75dd33e44083fe3e56

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Computational Theory and Mathematics

1. M. Namchuk
2. Jürgen Bajorath
3. W. Patrick Walters

In Environmental Chemistry

1. M. Namchuk
2. W. Patrick Walters

In Spectroscopy

1. M. Namchuk
2. Jürgen Bajorath
3. W. Patrick Walters

Citations in the corpus

• Integration of virtual and high-throughput screening (2002, background): “In addition, a pharmacophore filter has been developed that monitors preferred and undesired functional groups and detects drug-like molecules with about 30% greater frequency than synthetic compound”
• SwissADME: a free web tool to evaluate pharmacokinetics, drug-likeness and medicinal chemistry friendliness of small molecules (2017, neutral): “The Ghose (Amgen), Veber (GSK), Egan (Pharmacia) and Muegge (Bayer) methods were adapted from refs 58–61, respectively.”
• A guide to drug discovery: Designing screens: how to make your hits a hit (2003, methodology): “One example of this approach is the work of Muegge and co-worker”