Oxidation of pharmaceuticals during ozonation and advanced oxidation processes.

By M. Huber, S. Canonica, Gunyoung Park, U. von Gunten. Environmental Science and Technology, 2003

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This study investigates the oxidation of pharmaceuticals during conventional ozonation and advanced oxidation processes (AOPs) applied in drinking water treatment. In a first step, second-order rate constants for the reactions of selected pharmaceuticals with ozone (k(O3)) and OH radicals (k(OH)) were determined in bench-scale experiments (in brackets apparent k(O3) at pH 7 and T = 20 degrees C): bezafibrate (590 +/- 50 M(-1) s(-1)), carbamazepine (approximately 3 x 10(5) M(-1) s(-1)), diazepam (0.75 +/- 0.15 M(-1) s(-1)), diclofenac (approximately 1 x 10(6) M(-1) s(-1)), 17alpha-ethinylestradiol (approximately 3 x 10(6) M(-1) s(-1)), ibuprofen (9.6 +/- 1.0 M(-1) s(-1)), iopromide (<0.8 M(-1) s(-1)), sulfamethoxazole (approximately 2.5 x 10(6) M(-1) s(-1)), and roxithromycin (approximately 7 x 10(4) M(-1) s(-1)). For five of the pharmaceuticals the apparent k(O3) at pH 7 was >5 x 10(4) M(-1) s(-1), indicating that these compounds are completely transformed during ozonation processes. Values for k(OH) ranged from 3.3 to 9.8 x 10(9) M(-1) s(-1). Compared to other important micropollutants such as MTBE and atrazine, the selected pharmaceuticals reacted about two to three times faster with OH radicals. In the second part of the study, oxidation kinetics of the selected pharmaceuticals were investigated in ozonation experiments performed in different natural waters. It could be shown that the second-order rate constants determined in pure aqueous solution could be applied to predict the behavior of pharmaceuticals dissolved in natural waters. Overall it can be concluded that ozonation and AOPs are promising processes for an efficient removal of pharmaceuticals in drinking waters.

Subfields: Health, Toxicology and Mutagenesis, Pollution, Water Science and Technology

View Paper: https://www.semanticscholar.org/paper/2d90f09515210720ebae51b9d9dec8472f06bbd9

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Citations in the corpus

Removal of hazardous pollutants from wastewaters: applications of TiO 2 -SiO 2 mixed oxide materials (2014, background): “Even though chemical oxidation with ozone is considered as one of the effective techniques for treatment of wastewater, in some cases, ozone is used in combination with other treatments, particularly with biological treatment, to improve the degradation rate of pollutants [74, 101, 102, 104, 184, 18”
Pharmaceuticals as emerging contaminants and their removal from water. A review. (2013, background): “These radicals can generate numerous systems, making AOPs highly versatile (Brillas et al., 1998; Andreozzi et al., 1999; Huber et al., 2003; Esplugas et al., 2007; Baumgarten et al., 2007; Von Sonntag, 2008).”
Degradation and removal methods of antibiotics from aqueous matrices--a review. (2011, background): “Huber et al. (2003) 8.”
Occurrence and fate of pharmaceutical products and by-products, from resource to drinking water. (2009, neutral): “(2003), Huber et al. (2005), Ternes et al.”
Removal of residual pharmaceuticals from aqueous systems by advanced oxidation processes. (2009, background): “, 2005), hydrogen peroxide (Zwiener and Frimmel, 2000, Balcioglu and Otker, 2003; Huber et al., 2003; Arslan-Alaton et al., 2004; Arslan-Alaton and Caglayan, 2006) or with iron or copper complexes that act as catalysts (Skoumal et al.”