Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells.
By M. Salazar, Arkaitz Carracedo, Iñigo J. Salanueva, Sonia Hernández‐Tiedra, Mar Lorente, Ainara Egia, Patricia Vázquez, C. Blázquez, Sofía Torres, S. Garcia and 10 more. Journal of Clinical Investigation, 2009
691 citations recorded by the source corpus.
Subfields: Epidemiology, Geriatrics and Gerontology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/2cf243605bbb0fd96941f2d8c3b35b0ad54cde9d
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Citations in the corpus
- ER stress: Autophagy induction, inhibition and selection (2015, background): “Among those targets, MAPK8-mediated phosphorylation of BCL2 (B-cell CLL/ lymphoma 2) family of proteins such as pro-apoptotic BCL2 and BCL2L11/BIM promote cell death, whereas MAPK/p38 activation converges on a common cell death pathway induced by DDIT3.”
- Lysosomal membrane permeabilization and cell death (2018, background): “As lysosomes are the executors of the autophagy pathway, the inhibition of lysosomal activity may protect against cell death regulated by autophagy proteins.(128,129) While in most circumstances, autophagy is a cytoprotective pathway, in several pathophysiological conditions, autophagy contributes t”