The MAPK signalling pathways and colorectal cancer.

By J. Fang, B. Richardson. The Lancet Oncology, 2005

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p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents. (2014, background): “Once activated, MAPK exerts an important role in converting extracellular stimuli into a wide range of cellular responses, including proliferation, differentiation, senescence and so on [6–8].”
pathfindR: An R Package for Comprehensive Identification of Enriched Pathways in Omics Data Through Active Subnetworks (2019, background): “28760567 1 MAPK signaling plays an important part in progression of colorectal cancer (Fang and Richardson, 2005).”
A novel signaling pathway impact analysis (2009, methodology): “Several pathways are known to be relevant to the colorectal cancer, including the colorectal pathway itself, the PPAR signaling pathway (Shureiqi et al., 2003) and MAPK signaling pathway (Fang and Richardson, 2005).”
Current development of mTOR inhibitors as anticancer agents (2006, background): “and the mitogen-activated protein kinase (MAPK)/Ras signalling cascade”
Polyphenols and Human Health: Prevention of Disease and Mechanisms of Action (2010, background): “, MAPK kinase and PI3 Kinase), which are involved in cancer cell proliferation [61-63].”
Regulation of PD-L1: a novel role of pro-survival signalling in cancer. (2016, background): “The MAPK signalling pathway plays a critical role in cell survival and proliferation [47-49].”