Osteogenic Protein-1 (Bone Morphogenetic Protein-7) in the Treatment of Tibial Nonunions: A Prospective, Randomized Clinical Trial Comparing rhOP-1 with Fresh Bone Autograft*

By G. Friedlaender, C. Perry, J. Cole, S. Cook, G. Cierny, G. Muschler, G. Zych, J. Calhoun, A. J. Laforte, Samuel Yin. Journal of Bone and Joint Surgery. American volume, 2001

1,046 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Epidemiology, Urology

View Paper: https://www.semanticscholar.org/paper/2c96a1a750ff42365bde39cffbfb49c7eee6e856

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In Epidemiology

1. P. Giannoudis
2. T. Einhorn
3. Wenhao Wang
4. K. Yeung

Citations in the corpus

• Bone grafts, bone substitutes and orthobiologics (2012, background): “Evidence of healing in these difficult non-unions exceeded 75% in both control and BMP-7 groups.(21) Recently, BMP-7 has been approved as an alternative to autograft settings of long bone nonunions and in patients requiring revision posterior lumbar fusion procedures under the US FDA’s Humanitarian ”
• Bone substitutes in orthopaedic surgery: from basic science to clinical practice (2014, background): “Administration of growth factors and other bioactive molecules to promote bone formation and repair has achieved promising results in several preclinical and clinical models [120–125].”
• Recombinant Human Bone Morphogenetic Protein-2 for Treatment of Open Tibial Fractures: A Prospective, Controlled, Randomized Study of Four Hundred and Fifty Patients (2002, neutral): “of patients 150 151 149 Mean age (range)* (yr) 37 (17-87) 37 (17-78) 33 (18-77)”
• Fracture healing: the diamond concept. (2007, background): “J Bone Miner Res 1995; 10 1272-81 [15] Friedlaender GE, Perry CR, Cole JD, et al.”