Advances in homology protein structure modeling.

By Zhexin Xiang. 2006

461 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

AlphaFold2 and its applications in the fields of biology and medicine (2023, methodology): “18,19 The homology modeling method mainly uses two techniques: sequence alignment and molecular modeling.”
Structure-based Systems Biology for Analyzing Off-target Binding (2011, background): “Advances in structural genomics [25] and subsequent homology modeling [26] will continue to improve this coverage.”
Protein structure modeling with MODELLER. (2014, methodology): “Improving the performance and accuracy of methods in this regime remains one of the main tasks of comparative modeling(48,49).”
Homology Modeling a Fast Tool for Drug Discovery: Current Perspectives (2012, methodology): “Generally rigid-body assembly[45–47], segment matching[48], spatial restraint[49], and artificial evolution[50] are used for model building.”
Computational Methods in Drug Discovery (2014, methodology): “, 2012), Monte Carlo Metropolis minimization (Misura and Baker, 2005), or genetic algorithms (Xiang, 2006).”
Using PyMOL as a platform for computational drug design (2017, methodology): “35 To obtain reliable and accurate computational results, protein preparation is a compulsory step before any other molecular modeling task.”