The origin and evolution of cell types

By Detlev Arendt, J. Musser, C. V. Baker, Aviv Bergman, C. Cepko, Douglas H. Erwin, M. Pavličev, G. Schlosser, Stefanie Widder, Manfred D. Laubichler and 1 more. Nature reviews genetics, 2016

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Exponential scaling of single-cell RNA-seq in the past decade (2017, background): “Cells have traditionally been classified by their morphology or by expression of certain proteins in functionally distinct settings (Mosmann et al., 1986; Orkin, 2000; Poulin et al., 2016).”
The Human Transcription Factors. (2018, neutral): “This event is roughly coincident with the expansion of cell-type diversity, possibly facilitated by duplicated TFs available to regulate novel cell types (Nitta et al., 2015; Arendt et al., 2016).”
Single‐cell RNA sequencing technologies and applications: A brief overview (2022, methodology): “retained good quality cells using the following parameters: (1) 200 < total number of expressed genes per cell (nGenes) < 2500; (2) 300 < total number of UMIs”
Computational principles and challenges in single-cell data integration (2021, background): “An alternative approach could be to summarize gene expression profiles over gene sets or pathways, which might be better preserved by natural selection and thus provide a more robust anchor choice 98 .”