Realistic levels of inbreeding depression strongly affect extinction risk in wild populations

By J. O'Grady, Barry W. Brook, D. H. Reed, J. Ballou, D. Tonkyn, R. Frankham. 2006

614 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/2bf3dfaa90aa50a1f2ca93dd11d919d7d1eb9087

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

Citations in the corpus

Genetics in conservation management: Revised recommendations for the 50/500 rules, Red List criteria and population viability analyses (2014, background): “(see computations in Appendix A4) based on 12 diploid lethal equivalents in wild environments from the meta-analysis in O’Grady et al. (2006), while the 16 lethal equivalents value from Grueber et al. (2010) yields a decline of 33%.”
Inbreeding depression in ring-tailed lemurs (Lemur catta): genetic diversity predicts parasitism, immunocompetence, and survivorship (2008, background): “Inbreeding is most likely to occur in small populations and may contribute to the further decline and eventual extinction of threatened species (Gilpin and Soulé 1986; Saccheri et al. 1998; Hedrick 2001; O’Grady et al. 2006).”
Conservation genetics of population bottlenecks: the role of chance, selection, and history (2010, background): “That is, there is good evidence that small population size decreases genetic variation, and temporal studies on genetic diversity have demonstrated this, particularly at the molecular level (e.g., Bouzat et al. 1998; Hadly et al. 1998; Nielsen et al. 1999 ).”
Pragmatic population viability targets in a rapidly changing world (2010, critical): “Many use small impacts of inbreeding depression based on juvenile mortality in captive populations, rather than those for all components of reproduction and survival in wild populations (O’Grady et al., 2006).”
Bridging the conservation genetics gap by identifying barriers to implementation for conservation practitioners (2017, background): “Crucially, after decades of argument (e.g. Caro and Laurenson, 1994; Craig, 1994), it is now clear that genetic diversity and inbreeding can influence a species’ likelihood of extinction (Frankham, 2010;O’Grady et al., 2006).”
Demographic effects of temperature‐dependent sex determination: will tuatara survive global warming? (2010, methodology): “3 LE) reported in a survey of 30 studies of wild populations of mammals and birds (O’Grady et al., 2006).”
Where are we in conservation genetics and where do we need to go? (2010, background): “PVAs need to routinely include genetic factors, as inbreeding depression typically has sizeable impacts on median times to extinction (O’Grady et al. 2006).”