TLR3: interferon induction by double-stranded RNA including poly(I:C).

By Misako Matsumoto, Tsukasa Seya. Advanced Drug Delivery Reviews, 2008

711 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/2b8376ee1ddf0f4ed7ea38ea5ed88a7ad23cc50c

How researchers see this paper

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In Immunology

1. Kui Li
2. Sandra N. Lester
3. Danyang Li
4. Minghua Wu
5. Wenshuai Wang
6. Anna Marie Pyle

Citations in the corpus

• Pattern recognition receptors in health and diseases (2021, background): “It also interacts with TLR1–TLR2 in the same binding pocket as typical lipopeptide ligand.64 Crystal structure analysis revealed that double-stranded RNA (dsRNA) binds to the LRR domains of the N-terminus and Cterminus of TLR3.”
• Toll-like receptors in antiviral innate immunity (2013, background): “Poly I:C is a very potent synthetic analog of viral dsRNA and is widely used in scientific research to study TLR3-mediated antiviral responses [217].”