Hippocampal Granule Neuron Number and Dentate Gyrus Volume in Antidepressant-Treated and Untreated Major Depression

By M. Boldrini, Adrienne N Santiago, R. Hen, A. Dwork, G. Rosoklija, H. Tamir, V. Arango, J. Mann. 2013

323 citations recorded by the source corpus.

Subfields: Behavioral Neuroscience, Cellular and Molecular Neuroscience, Developmental Neuroscience

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Behavioral Neuroscience

1. R. Hen
2. Dharshan Kumaran
3. Melody V. Wu

In Cellular and Molecular Neuroscience

1. Melody V. Wu
2. R. Hen
3. Arturo Cárdenas-Blanco
4. J. Frisén
5. Dharshan Kumaran
6. Hugo J. Kuijf
7. Emrah Düzel
8. Hartmut Schütze

In Developmental Neuroscience

1. R. Hen
2. Melody V. Wu
3. K. Spalding
4. J. Frisén
5. O. Bergmann
6. Dharshan Kumaran
7. Fred H. Gage
8. Hongjun Song

Citations in the corpus

• Human Hippocampal Neurogenesis Persists throughout Aging (2018, neutral): “There was no age-related change in the number of NeuN+ GNs or Nissl+ glia estimated using stereology, nor in the volume of the DG or the GCL-SGZ in anterior, mid, and posterior hippocampus of both genders (Figures 3E–3F, 3H, and 3I and Figures 4H and 4I; Video S4), as estimated using the Cavalieri m”
• Adult Neurogenesis in Humans. (2015, background): “To assess whether a decrease in hippocampal DG volume in antidepressant treated and untreated individuals suffering from MDD is a result of decreased neurogenesis, mature granule neuron number and DG and granule cell layer volume were determined (Boldrini et al. 2013).”
• Strong Evidence for Pattern Separation in Human Dentate Gyrus (2016, background): “A single voxel in our study would contain 30,000 granule neurons, whereas this would have been 200,000 per voxel in earlier high-resolution studies at 3 T (Boldrini et al., 2013).”
• Functional Dissociation of Adult-Born Neurons Along the Dorsoventral Axis of the Dentate Gyrus (2014, background): “…administration has also been shown to result in increased numbers of neural progenitors and mature granule cells specifically in the rostral (homologous to the ventral in rodents) dentate gyrus granule cell layer of depressed patients compared to untreated controls (Boldrini et al., 2012, 2013).”
• Benzodiazepines And The Potential Trophic Effect Of Antidepressants On Dentate Gyrus Cells In Mood Disorders (2014, unknown): “Immunohistochemistry and stereology were performed as previously described (Boldrini et al., 2009, 2012, 2013).”