GPCR Dynamics: Structures in Motion.

By Naomi R. Latorraca, A. Venkatakrishnan, Ron O. Dror. 2017

713 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Radiology, Nuclear Medicine and Imaging

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Ron O. Dror

In Molecular Biology

1. A. Venkatakrishnan
2. Ron O. Dror
3. Sriram Kosuri
4. Naomi R. Latorraca

In Radiology, Nuclear Medicine and Imaging

1. Ron O. Dror

Citations in the corpus

• AlphaFold2 versus experimental structures: evaluation on G protein-coupled receptors (2022, background): “Considering that GPCRs are highly dynamic proteins, more than one ECD-TMD assemblies may exist for a particular receptor [23, 29].”
• Structural and functional characterization of G protein–coupled receptors with deep mutational scanning (2019, background): “Tools such as double electron-electron resonance (DEER) spectroscopy, nuclear magnetic resonance (NMR) spectroscopy, and computational simulation have aided our understanding of GPCR dynamics, but interpreting how structural dynamics relate to function is still difficult (Latorraca et al., 2017; Man”