An integrated computational/experimental model of tumor invasion.
By Hermann B. Frieboes, Xiaoming Zheng, Chung-ho Sun, Bruce J. Tromberg, Robert A. Gatenby, Vittorio Cristini. Cancer Research, 2006
304 citations recorded by the source corpus.
Subfields: Cell Biology, Modeling and Simulation, Oncology
View Paper: https://www.semanticscholar.org/paper/2ade4ba095ec2071703e2d84113b7dcf084a3bad
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Citations in the corpus
- Modeling tissue morphogenesis and cancer in 3D. (2007, unknown): “…more effectively than regular 2D cell cultures because spheroids, much like tumors, usually contain both surface-exposed and deeply buried cells, proliferating and nonproliferating cells, and well-oxygenated and hypoxic cells (the latter secreting tumor cell cytokines; Frieboes et al., 2006).”
- Three-dimensional multispecies nonlinear tumor growth--I Model and numerical method. (2008, background): “4c which is taken from Frieboes et al. (2006).”
- Toward an Ising Model of Cancer and Beyond (2010, unknown): “Such modeling of tumor growth using a variety of different approaches has been a very active area of research for the last two decades or so [6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24] but clearly is in its infancy.”
- Tumor morphology and phenotypic evolution driven by selective pressure from the microenvironment. (2006, result): “This concept is consistent with and may help explain experimental and clinical findings showing that hypoxia or nutrient deprivation leads to invasive, aggressive tumor behavior (Casanovas et al., 2005; Erler et al., 2006; Frieboes et al., 2006; Kerbel, 1990; Pennacchietti et al., 2003).”
- 2D and 3D cell cultures – a comparison of different types of cancer cell cultures (2016, background): “Access to essential compounds Unlimited access to oxygen, nutrients, metabolites and signalling molecules (in contrast to in vivo) Variable access to oxygen, nutrients, metabolites and signalling molecules (same as in vivo) [10, 46]”