The neurobiology of itch
By A. Ikoma, M. Steinhoff, S. Ständer, G. Yosipovitch, M. Schmelz. Nature Reviews Neuroscience, 2006
960 citations recorded by the source corpus.
Subfields: Dermatology, Physiology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/2a8b640d145b627afbc9f90aa00cda9330afaff0
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In Physiology
Citations in the corpus
- The Epithelial Cell-derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch (2013, positive): “Itch is mediated by primary afferent somatosensory neurons that havecell bodies in thedorsal rootganglia (DRG) that innervate the skin andareactivatedbyendogenouspruritogens todrive itch behaviors (Ikoma et al., 2006; McCoy et al., 2012; Ross, 2011).”
- TRPA1 is required for histamine-independent, Mas-related G protein-coupled receptor-mediated itch (2011, neutral): “Approximately 5–20% of primary afferent C-fibers are activated by endogenous itch-producing compounds released by non-neuronal cells in the skin (e.g., mast cells), as well as by exogenous pruritogens, such as chloroquine 1, 15, 16 .”
- Histamine in the nervous system. (2008, background): “Cutaneous itch is mediated by C-fibers distinct from those subserving pain sensation (278) (see sect.”