Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation

By E. Papapetrou, M. Tomishima, S. M. Chambers, Yvonne Mica, E. Reed, J. Menon, V.R.a Tabar, Q. Mo, L. Studer, Michel Sadelain. 2009

299 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomedical Engineering

1. James J. Collins

In Molecular Biology

1. James J. Collins
2. Dimiter S. Dimitrov
3. Yuin Han Loh
4. Alexander Meissner
5. G. Daley
6. Zachary D. Smith
7. Derrick J. Rossi
8. Michel Sadelain

Citations in the corpus

• Highly efficient reprogramming to pluripotency and directed differentiation of human cells using synthetic modified mRNA (2010, methodology): “Lowoxygen (5% O2) culture conditions and a KMOS stoichiometry of 1:1:3:1 were employed, because these have been reported to promote efficient iPSC conversion (Kawamura et al., 2009; Papapetrou et al., 2009; Utikal et al., 2009; Yoshida et al., 2009).”
• Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition. (2016, background): “DNR, the mCherry fluorescent protein reporter (68, 69).”