Working memory revived in older adults by synchronizing rhythmic brain circuits

By R. Reinhart, John A. Nguyen. 2019

Subfields: Aging, Cognitive Neuroscience

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Citations in the corpus

Rhythms of human attention and memory: An embedded process perspective (2022, methodology): “…of theta-gamma coupling processes in WM comes from a study by Alekseichuk et al. (2016), who enhanced WM performance by theta-gamma stimulation protocols, and empirical ﬁndings that WM capacities can be revived by a theta-gamma stimulation applied in elder participants (Reinhart and Nguyen, 2019).”
Multimodal neuroimaging of hierarchical cognitive control. (2024, methodology): “…which are typically approximately 5-by-5 cm in size (Ahn et al., 2019; Riddle et al., 2021; Violante et al., 2017), although recent techniques using high-definition tACS use 1 cm 2 electrodes with electric fields on the order of a few cm (Alekseichuk et al., 2016; Reinhart & Nguyen, 2019).”
Haemodynamic correlates of bilateral 6 Hz transcranial alternating current stimulation during working memory enhancement revealed by fNIRS (2026, unknown): “…and Nguyen showed that individualized theta-frequency HD-tACS improved change-detection accuracy with minimal eﬀects on reaction time in healthy younger adults and, critically, restored performance in healthy older adults, consistent with enhanced processing eﬃciency (Reinhart and Nguyen, 2019).”
No effects of the theta-frequency transcranial electrical stimulation for recall, attention control, and relation integration in working memory (2024, background): “…et al., 2018; Pahor and Jaušovec, 2018; Röhner et al., 2018; Tseng et al., 2018; Wolinski et al., 2018; Bender et al., 2019; Jones et al., 2019; Reinhart and Nguyen, 2019; Abellaneda-Pérez et al., 2020; Guo et al., 2021; Hosseinian et al., 2021; Sahu and Tseng, 2021; Biel et al., 2022;…”
Neurovascular coupling in the attention during visual working memory processes (2024, background): “53 Our oscillatory results showed that there was a greater increase in the frontal theta power as target or distractor items increased.”
Neural signatures of competition between voluntary and involuntary influences over the focus of attention in visual working memory (2023, methodology): “…magnetic stimulation or transcranial alternating-current stimulation) delivered in theta range to frontal midline cortex has been shown to improve working-memory performance (Riddle, Scimeca, Cellier, Dhanani, & D ’ Esposito, 2020; Reinhart & Nguyen, 2019; Zakrzewska & Brzezicka, 2014).”
The neurovascular coupling in the attention during visual working memory (2023, background): “The NVC with frontal theta activities 3 Frontal theta oscillations play a causal role in facilitating increases in vWM capacity, which 4 are thought to have links with frontal theta power [32, 63] or with theta synchronizations [64].”
Closing the loop between brain and electrical stimulation: towards precision neuromodulation treatments (2023, methodology): “Therefore, frontoparietal synchronization is a candidate target. b. Stimulator: Inspired by previous frontoparietal synchronization studies [185, 186], tACS in the theta (4 – 8 Hz) frequency range (as an initial value for the ﬁ rst iteration) to induce synchronized brain oscillations between…”
How structural and functional MRI can inform dual-site tACS parameters: A case study in a clinical population and its pragmatic implications. (2022, methodology): “Furthermore, different current intensity was used in each stimulation site to have similar EF magnitude in the targeted brain regions [60,100].”
Phase synchronized 6 Hz transcranial electric and magnetic stimulation boosts frontal theta activity and enhances working memory (2021, background): “Similarly, einhart and Nguyen (2019) recently demonstrated enhancement in orking memory in older adults through network stimulation and synhronization of fronto-temporal cortices using tACS in the theta range, lthough effects were dependent on the ability to achieve precise align- ent of the externa”