The origin of consistent protein structure refinement from structural averaging.
By Hahnbeom Park, Frank DiMaio, David Baker. 2015
17 citations recorded by the source corpus.
Subfields: Atomic and Molecular Physics, and Optics, Materials Chemistry, Molecular Biology
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Atomic and Molecular Physics, and Optics
In Materials Chemistry
In Molecular Biology
Citations in the corpus
- High-accuracy refinement using Rosetta in CASP13 (2019, methodology): “…93 and C α -RMSD of 0.48 Å. Post analysis on this target indicated a complementary role of Rosetta and explicit water MD as observed previously 2,21,22 : while Rosetta successfully recovered a critical error at the C-terminus and side-chain orientations around it, MD successfully brought the…”
- Toward the solution of the protein structure prediction problem (2021, background): “While rigorous theoretical studies to explain the consistent improvement brought about by combining multiple structures were not available until many years later (100), the intuition behind the usage of multiple threading templates is simple.”
- Computational protein structure refinement: Almost there, yet still so far to go (2017, background): “62,175”
- Experimental accuracy in protein structure refinement via molecular dynamics simulations (2018, background): “In practice, such a protocol works best when selected ensemble subsets are averaged to match the nature of experimental structures and reduce scoring function noise (27, 28).”