Clinical correlates and prognostic significance of six-minute walk test in patients with primary pulmonary hypertension. Comparison with cardiopulmonary exercise testing.

By S. Miyamoto, N. Nagaya, T. Satoh, S. Kyotani, F. Sakamaki, M. Fujita, N. Nakanishi, K. Miyatake. American Journal of Respiratory and Critical Care Medicine, 2000

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Continuous subcutaneous infusion of treprostinil, a prostacyclin analogue, in patients with pulmonary arterial hypertension: a double-blind, randomized, placebo-controlled trial. (2002, background): “It appears that such patients are remarkably stable, at least over a three-month period of time, with modest changes in exercise capacity, and a mortality of only 3%. This mortality rate after a relatively short observation period of only three months was actually expected on the basis of both the s”
Pulmonary arterial hypertension in France: results from a national registry. (2006, methodology): “The 6-min walk test is a submaximal exercise test that can be performed by patients incapable of tolerating maximal exercise testing (15).”
Sarcopenia With Limited Mobility: An International Consensus (2011, background): “406 Morley et al a clinically significant change has been found to be more than 50 meters.(69,76,77) (There was a viewpoint among the panel that this may be better expressed as a percentage of baseline.”