By binding SIRPalpha or calreticulin/CD91, lung collectins act as dual function surveillance molecules to suppress or enhance inflammation.

By S. Gardai, Y. Xiao, Matthew Dickinson, J. Nick, D. Voelker, K. Greene, P. Henson. Cell, 2003

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Immunoregulatory functions of surfactant proteins (2005, background): “fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=4035">CD91 is a component of the binding comple”
Phagocytosis of Staphylococcus aureus by human neutrophils prevents macrophage efferocytosis and induces programmed necrosis (2014, background): “inhibits SIRPa signaling and promotes efferocytosis (17, 18).”