Initiation and Synergistic Fibrillization of Tau and Alpha-Synuclein

By B. Giasson, M. Forman, M. Higuchi, L. Golbe, C. L. Graves, P. Kotzbauer, John Q. Trojanowski, V. Lee. Science, 2003

908 citations recorded by the source corpus.

Subfields: Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/26efbdef027d287884feb1556445394d3cc723f6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Neurology

1. Valina L. Dawson
2. T. Dawson
3. Leonidas Stefanis
4. V. Lee
5. John Q. Trojanowski
6. Trevor W. Robbins
7. Roger A. Barker
8. Daniel R. Weinberger

In Physiology

1. V. Lee
2. John Q. Trojanowski
3. Leonidas Stefanis
4. Louise C. Serpell
5. William W. Seeley
6. Valina L. Dawson
7. T. Dawson
8. M. Goedert

Citations in the corpus

• Distinct tau prion strains propagate in cells and mice and define different tauopathies (2014, background): “Prior reports have indicated that in certain cases, a-synuclein aggregates can cross-seed FL tau (Giasson et al., 2003; Guo et al., 2013;Waxman and Giasson, 2011).”
• The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort. (2009, background): “Third, tau and alpha-synuclein have been shown to interact and fibrillize synergistically in vitro (Giasson et al., 2003).”
• Role of tau protein in both physiological and pathological conditions. (2004, background): “Avila, unpublished data), and -synuclein has also been seen to facilitate tau assembly (79).”