Prevalence, consequence, and significance of reverse cleavage by human embryos viewed with the use of the Embryoscope time-lapse video system.

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Ethical Implementation of Artificial Intelligence to Select Embryos in In Vitro Fertilization (2021, background): “However, the availability of numerous data points made available by recent advances, such as with time-lapse videography [10], has enabled novel parameters to be measured for embryo selection [11, 12, 13].”
Between-laboratory reproducibility of time-lapse embryo selection using qualitative and quantitative parameters: a systematic review and meta-analysis (2020, methodology): “Examples of these parameters include (i) direct cleavage (DC) where one blastomere directly divides into three or more daughter blastomeres [11], (ii) reverse cleavage (RC) where blastomeres either fuse after cleavage or lead to failed cytokinesis following karyokinesis [12], (iii) chaotic cleavage ”
Time-lapse deselection model for human day 3 in vitro fertilization embryos: the combination of qualitative and quantitative measures of embryo growth. (2016, background): “, MN formation after RC as illustrated in a previously published video clip [19]), and its impact could be diluted by the inclusion of such parameters.”
Assessing efficacy of day 3 embryo time-lapse algorithms retrospectively: impacts of dataset type and confounding factors (2019, methodology): “To overcome this, a number of qualitative measures have been reported in recent years for embryo deselection (Athayde Wirka et al., 2014; Liu et al., 2014; Liu et al., 2015a; Rubio et al., 2012).”