Liver stiffness measurement predicts severe portal hypertension in patients with HCV‐related cirrhosis

By F. Vizzutti, U. Arena, R. Romanelli, L. Rega, M. Foschi, S. Colagrande, A. Petrarca, S. Moscarella, G. Belli, A. Zignego and 3 more. Hepatology, 2007

734 citations recorded by the source corpus.

Subfields: Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/26822d5ff4462cb5bf141f38a177e8b47eeb59a8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Laurent Castéra
2. Asociacion Latinoamericana para el Estudio del Higado
3. X. Forns

In Hepatology

1. Laurent Castéra
2. Asociacion Latinoamericana para el Estudio del Higado
3. F. Piscaglia
4. X. Forns

Citations in the corpus

• Non-invasive evaluation of liver fibrosis using transient elastography. (2008, background): “3 kPa, sensitivity for the prediction of the presence of OV was high (95%, 90%, and 79%, respectively) but specificity was rather low (43%, 43%, and 70%, respectively) [38,51,52].”
• UK guidelines on the management of variceal haemorrhage in cirrhotic patients (2000, methodology): “Vizzutti et al 32 in a study of 61 patients with hepatitis C showed a sensitivity for prediction of oesophageal varices of 90% using a threshold 17.6 kPa.”
• Noninvasive assessment of liver fibrosis (2011, background): “A study that included 165 patients with cirrhosis demonstrated that liver stiffness values below 19 kPa were highly predictive of the absence of large varices, with a negative predictive value of 93%.60 Other studies have reached similar conclusions.61 It is important to remember, however, that the ”
• EASL-ALEH Clinical Practice Guidelines: Non-invasive tests for evaluation of liver disease severity and prognosis. (2015, background): “Several studies have shown that there is a good correlation between LS values and HVPG in patients with advanced liver diseases in both pre- and post-transplant settings [285–288].”
• EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography.Part 2: Clinical Applications (2013, positive): “The AUROCs for predicting clinically significant portal hypertension (hepatic venous pressure gradient ≥ 12mmHg), were 0.94 – 0.99 for cut-offs ranging from 13.6 to 21 kPa [29, 30].”