Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits.

By K. Hynynen, N. McDannold, N. Vykhodtseva, F. Jolesz. Radiology, 2001

1,404 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Cellular and Molecular Neuroscience, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/2624e5ad0c65f10bc2857c83353b3d5d1e1ba800

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1. N. McDannold
2. K. Hynynen
3. F. Jolesz
4. N. Sheikov
5. N. Vykhodtseva

Citations in the corpus

• Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications (2005, methodology): “…10 s before each sonication, a bolus (0.05 ml/kg) of ultrasound contrast agent (Optison, Mallinckrodt Inc., St. Louis, MO) that contains albumin coated microbubbles (mean diameter = 2.0–4.5 Â 10 À6 m; concentration = 5–8 Â 10 8 bubbles/ml) was injected into the ear vein (Hynynen et al., 2001).”