Apolipoprotein E: far more than a lipid transport protein.

By R. Mahley, S. C. Rall. Annual review of genomics and human genetics (Print), 2000

1,791 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Association of apolipoprotein E genotypes with lipid levels and coronary risk. (2007, neutral): “(Bycontrast, about5%ofε2/ε2 homozygotes develop type III hyperlipoproteinemia, a disorder characterizedbyincreased levelsofcholesteroland triglycerides and premature cardiovascular disease.(170)) The differing effects of differentapoEgenotypesoncoronaryrisk might also be explained by influences on a”
Distinct patterns of brain activity in young carriers of the APOE-ε4 allele (2009, background): “A E (apoE, protein; APOE, gene) is a very-lowdensity lipoprotein that removes cholesterol from the blood and carries it to the liver for processing (1).”
Progesterone receptors: form and function in brain. (2008, neutral): “In astrocytes, P4 regulates production of multiple proteins including those shown to be involved in regulating synaptic plasticity such as ApoE which is secreted by astrocytes may be an important player in synaptic remodeling, since this protein transports cholesterol and other lipids to outgrowing ”