The Reward Deficiency Syndrome: A Biogenetic Model for the Diagnosis and Treatment of Impulsive, Addictive and Compulsive Behaviors

By K. Blum, E. Braverman, Jay M. Holder, Joel F. Lubar, V. Monastra, David K. Miller, J. Lubar, Thomas J. H. Chen, D. Comings. Journal of Psychoactive Drugs, 2000

964 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/2556d05497b1f4c8f209c9cdbd3e07bbc65c9586

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In Cellular and Molecular Neuroscience

In Molecular Biology

In Psychiatry and Mental health

Citations in the corpus

Alcohol: Effects on Neurobehavioral Functions and the Brain (2007, background): “Other studies have revealed an association between certain dopaminergic gene polymorphisms and a number of reward dependent behaviors including addictive, compulsive, and impulsive tendencies (Blum et al. 2000).”
The role of impulsivity in the development of substance use and eating disorders. (2004, neutral): “[24].”
The Adolescent Brain (2008, background): “What might explain individual differences in decision making and behavior? Some theorists have postulated that the dopaminergic mesolimbic circuitry, implicated in reward processing, underlies risky behavior (Blum et al. 2000), and that individual differences in this circuitry might relate to the pr”
The Experience of Gambling and its Role in Problem Gambling (2006, background): “In the third analysis we assume that impulsivity is a relatively stable trait that preexists gambling problems and is based on physiological differences in the reward system of the brain (Blum et al., 2000).”
Partisanship, Voting, and the Dopamine D2 Receptor Gene (2009, background): “This quality has resulted in dopamine being dubbed the ‘‘antistress molecule’’ (Blum et al. 2000).”
The brain opioid theory of social attachment: a review of the evidence (2011, background): “Similarly, heightened levels of fi endorphin have been associated with acupuncture and this therapy has been found to have positive effects with respect to the rehabilitation of opiate ad dicts (Blum et al., 2000).”
Pathways to Pathological Gambling: Component Analysis of Variables Related to Pathological Gambling (2008, neutral): “Numerous theories have been proposed to account for disordered gambling including behavioural (Skinner, 1953), cognitive (e.g. Ladouceur & Walker, 1996), genetic (Blum et al., 2000), and emotion-based theories (Gupta & Derevensky, 1998a,b).”
A pathways model of problem and pathological gambling. (2002, background): “It is hypothesized that a lack of D2 receptors cause individuals to seek pleasure-generating activities, placing them at high risk for multiple addictive, impulsive and compulsive behaviours, including substance abuse, binge eating, sex addiction and pathological gambling (Blum et al. 2000).”