Dr. Pangloss restrained by the Red Queen : steps towards a unified defence theory

By J. Jokela, P. Schmid-Hempel, M. Rigby. 2000

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Evolutionary Causes and Consequences of Immunopathology (2005, background): “Integration of the influences of the efficacy and specificity of responses is certainly an important step toward a “unified defense theory” (Jokela et al. 2000), but evolutionary studies as yet largely omit investigation of immune response efficacy.”
Immune Defense and Host Life History (2002, background): “These two aspects of costs (diversity of parasites being most related to option costs, elimination of parasites being resource costly) are addressed in a model by Jokela et al. (2000).”
Variation in immune defence as a question of evolutionary ecology (2003, background): “Remarkably few attempts have been made to integrate these two major sources of variation in immune response, i.e. costly trade-offs and specificity, into a common framework (Frank 2000; Jokela et al. 2000).”